A Case of Methotrexate Intoxication Misdiagnosed as Crimean-Congo Hemorrhagic Fever

Authors

  • Mehdi Fazlalipour Department of Arboviruses and Viral Hemorrhagic Fevers (National Reference Laboratory), Pasteur Institute of Iran, Tehran, Iran
  • Mohammad Hassan Pouriayevali Department of Arboviruses and Viral Hemorrhagic Fevers (National Reference Laboratory), Pasteur Institute of Iran, Tehran, Iran
  • Mostafa Salehi-Vaziri Department of Arboviruses and Viral Hemorrhagic Fevers (National Reference Laboratory), Pasteur Institute of Iran, Tehran, Iran
  • Motahareh Hosseini Department of Arboviruses and Viral Hemorrhagic Fevers (National Reference Laboratory), Pasteur Institute of Iran, Tehran, Iran
  • Sahar Khakifirouz Department of Arboviruses and Viral Hemorrhagic Fevers (National Reference Laboratory), Pasteur Institute of Iran, Tehran, Iran
  • Sanam Azad-Manjiri Department of Arboviruses and Viral Hemorrhagic Fevers (National Reference Laboratory), Pasteur Institute of Iran, Tehran, Iran
  • Sara Azizizadeh Department of Arboviruses and Viral Hemorrhagic Fevers (National Reference Laboratory), Pasteur Institute of Iran, Tehran, Iran
  • Tahereh Mohammadi Department of Arboviruses and Viral Hemorrhagic Fevers (National Reference Laboratory), Pasteur Institute of Iran, Tehran, Iran
  • Tahmineh Jalali Department of Arboviruses and Viral Hemorrhagic Fevers (National Reference Laboratory), Pasteur Institute of Iran, Tehran, Iran
  • Vahid Baniasadi Department of Arboviruses and Viral Hemorrhagic Fevers (National Reference Laboratory), Pasteur Institute of Iran, Tehran, Iran
  • Yasaman Jamshidi Department of Arboviruses and Viral Hemorrhagic Fevers (National Reference Laboratory), Pasteur Institute of Iran, Tehran, Iran
Abstract:

[No Abstract] Crimean-Congo hemorrhagic fever (CCHF) is considered as the most important arboviral infection in Iran. Early diagnosis of CCHF is essential for preventing the spread of the infection and providing appropriate treatment to patients. Given that clinical symptoms of CCHF may overlap with other common infectious disease; differential diagnosis is a matter of great importance. In this report, we describe a case of rheumatoid arthritis intoxicated with methotrexate mimicking CCHF. This observation suggests that non-infectious medical conditions such as drug toxicity should be considered as a possible differential diagnosis of CCHF.

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Journal title

volume 4  issue 1

pages  37- 38

publication date 2016-01

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